Anthropic said on Nov. 4 that Claude helped its biology team map what the company calls the first 3D structure of a prokaryotic vault, built in E. coli from 96 copies of a bacteriophage protein it names L05. The blog puts the shell at about 9.5 megadaltons and roughly 54 by 45 nanometers, enclosing about 25 percent more volume than a mammalian vault; the hosted preprint reports a nominal resolution of 3.2 angstroms and a short-axis width of 47.5 nanometers. The particles have not been shown in their native hosts, their function is unknown, and the bioRxiv link was not yet live.
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